What is Lyrica (pregabalin) and what is it used for?

Lyrica is a prescription medicine used in adults, 18 years of age and older to treat: Buy Lyrica pregabalin online in New Zealand and Australia

• pain from damaged nerves (neuropathic pain) that happens with diabetes
• pain from damaged nerves (neuropathic pain) that follows healing of shingles
• fibromyalgia (pain all over your body)
• pain from damaged nerves (neuropathic pain) that follows spinal cord injury

It is not known if Lyrica is safe and effective in people under 18 years of age for the treatment of fibromyalgia and neuropathic pain with diabetes, shingles, or spinal cord injury. Buy Lyrica pregabalin online in New Zealand and Australia

Lyrica is a prescription medicine used in people 1 month of age and older to treat:

• partial-onset seizures when taken together with other seizure medicines.

For the treatment of partial-onset seizures when taken together with other seizure medicines, it is not known if Lyrica is safe and effective in children under 1 month of age.

What are side effects and other important information about Lyrica?

Lyrica may cause serious side effects including:

• serious, even life-threatening, allergic reactions
• swelling of your hands, legs and feet
• suicidal thoughts or actions
• serious breathing problems
• dizziness and sleepiness

INDICATIONS

LYRICA is indicated for: Buy Lyrica pregabalin online in New Zealand and Australia

• Management of neuropathic pain associated with diabetic peripheral neuropathy
• Management of postherpetic neuralgia
• Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
• Management of fibromyalgia
• Management of neuropathic pain associated with spinal cord injury

DOSAGE AND ADMINISTRATION

Important Administration Instructions

LYRICA is given orally with or without food.

When discontinuing LYRICA, taper gradually over a minimum of 1 week [see WARNINGS AND PRECAUTIONS].

Because LYRICA is eliminated primarily by renal excretion, adjust the dose in adult patients with reduced renal function [see Dosing For Adult Patients With Renal Impairment]. Buy Lyrica pregabalin online in New Zealand and Australia

Neuropathic Pain Associated With Diabetic Peripheral Neuropathy In Adults

The maximum recommended dose of LYRICA is 100 mg three times a day (300 mg/day) in patients with creatinine clearance of at least 60 mL/min. Begin dosing at 50 mg three times a day (150 mg/day). The dose may be increased to 300 mg/day within 1 week based on efficacy and tolerability.

Although LYRICA was also studied at 600 mg/day, there is no evidence that this dose confers additional significant benefit and this dose was less well tolerated. In view of the dose-dependent adverse reactions, treatment with doses above 300 mg/day is not recommended [see ADVERSE REACTIONS]. Buy Lyrica pregabalin online in New Zealand and Australia

Postherpetic Neuralgia In Adults

The recommended dose of LYRICA is 75 to 150 mg two times a day, or 50 to 100 mg three times a day (150 to 300 mg/day) in patients with creatinine clearance of at least 60 mL/min. Begin dosing at 75 mg two times a day, or 50 mg three times a day (150 mg/day). The dose may be increased to 300 mg/day within 1 week based on efficacy and tolerability. Buy Lyrica pregabalin online in New Zealand and Australia

Patients who do not experience sufficient pain relief following 2 to 4 weeks of treatment with 300 mg/day, and who are able to tolerate LYRICA, may be treated with up to 300 mg two times a day, or 200 mg three times a day (600 mg/day). In view of the dose-dependent adverse reactions and the higher rate of treatment discontinuation due to adverse reactions, reserve dosing above 300 mg/day for those patients who have on-going pain and are tolerating 300 mg daily [see ADVERSE REACTIONS].

Adjunctive Therapy For Partial-Onset Seizures In Patients 1 Month Of Age And Older

The recommended dosages for adults and pediatric patients 1 month of age and older are included in Table 1. Administer the total daily dosage orally in two or three divided doses as indicated in Table 1. In pediatric patients, the recommended dosing regimen is dependent upon body weight. Based on clinical response and tolerability, dosage may be increased, approximately weekly. Buy Lyrica pregabalin online in New Zealand and Australia

Table 1. Recommended Dosage for Adults and Pediatric Patients 1 Month and Older

 

Age and Body Weight	Recommended Initial Dosage	Recommended Maximum Dosage	Frequency of Administration
Adults (17 years and older)	150 mg/day	600 mg/day	2 or 3 divided doses
Pediatric patients weighing 30 kg or more	2.5 mg/kg/day	10 mg/kg/day (not to exceed 600 mg/day)	2 or 3 divided doses
Pediatric patients weighing less than 30 kg	3.5 mg/kg/day	14 mg/kg/day	1 month to less than 4 years of age: 3 divided doses4 years of age and older: 2 or 3 divided doses

 

Both the efficacy and adverse event profiles of LYRICA have been shown to be dose-related.

The effect of dose escalation rate on the tolerability of LYRICA has not been formally studied.

The efficacy of adjunctive LYRICA in patients taking gabapentin has not been evaluated in controlled trials. Consequently, dosing recommendations for the use of LYRICA with gabapentin cannot be offered. Buy Lyrica pregabalin online in New Zealand and Australia

Management Of Fibromyalgia In Adults

The recommended dose of LYRICA for fibromyalgia is 300 to 450 mg/day. Begin dosing at 75 mg two times a day (150 mg/day). The dose may be increased to 150 mg two times a day (300 mg/day) within 1 week based on efficacy and tolerability. Patients who do not experience sufficient benefit with 300 mg/day may be further increased to 225 mg two times a day (450 mg/day). Although LYRICA was also studied at 600 mg/day, there is no evidence that this dose confers additional benefit and this dose was less well tolerated. In view of the dose-dependent adverse reactions, treatment with doses above 450 mg/day is not recommended